Med Decis Making. 2008 Mar 18;
Schackman BR, Teixeira PA, Weitzman G, Mushlin AI, Jacobson IM
BACKGROUND: Chronic hepatitis C (HCV) treatment is initiated infrequently by patients in urban settings. These patients often decline HCV treatment due to concerns about treatment side effects and have communication problems with their physicians. METHODS: . The authors investigated differences between how patients and providers evaluate the quality-of-life tradeoffs associated with HCV treatment in computer-assisted interviews. They interviewed 92 treatment-naive HCV patients at gastroenterology, methadone maintenance, and HIV clinics at 3 hospitals in New York City and 23 physicians or nurses experienced in treating HCV at other hospitals in New York City. Subjects completed rating scale and standard gamble evaluations of current health and hypothetical descriptions of HCV symptoms and treatment side effects on a scale from 0 (death or worse than death) to 1 (best possible health). RESULTS: . Treatment side effects were rated worse by patients than providers using the rating scale (moderate side effects 0.42 v. 0.62; severe side effects 0.24 v. 0.40) and standard gamble (moderate side effects 0.61 v. 0.91; severe side effects 0.52 v. 0.75) (all P
